p53 / APC / 9L526
p53 / APC / 9L526
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | P1001-30E-APC-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $628.00 | |
| Antigen | p53 | |
| Clone | 9L526 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | APC | |
| Target Species | Human | |
| Applications | ELISA | |
| Description | p53 (Tumor Suppressor Protein, Oncogene Protein) (APC) Mab 9L526 |
About p53 and APC
| p53 | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
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