p53 / MaxLight 650 /
p53 / MaxLight 650 /
Product Details
Supplier | US Biological | |
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Catalog #: | P1001-27M-ML650-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $711.00 | |
Antigen | p53 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | MaxLight 650 | |
Target Species | Human | |
Applications | FC, WB | |
Description | p53 (T55) (Cellular Tumor Antigen p53, Tumor Suppressor p53, Phosphoprotein p53, Antigen NY-CO-13, TP53, P53) (MaxLight 650) Pab |
About p53 and MaxLight 650
p53 | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] | |
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MaxLight 650 | MaxLight 650 is excited by the 640 laser and emission captured by the 670/30 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy. |