p53 / MaxLight 490 / BP53-12
p53 / MaxLight 490 / BP53-12
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 138582-AF-ML490-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $694.00 | |
| Antigen | p53 | |
| Clone | BP53-12 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | MaxLight 490 | |
| Target Species | Human | |
| Applications | FC, IF, IHC, IP, WB | |
| Description | p53 (Tumor Suppressor Protein, Oncogene Protein) (MaxLight 490) Mab BP53-12 |
About p53 and MaxLight 490
| p53 | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] | |
|---|---|---|
| MaxLight 490 | MaxLight 490 is excited by the 488 laser and emission captured by the 515/30 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy. |
Citations
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