Protein Disulfide Isomerase / Biotin /
Protein Disulfide Isomerase / Biotin /
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 130803-Biotin-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $718.00 | |
| Antigen | Protein Disulfide Isomerase | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | WB | |
| Description | P4HB (Protein Disulfide-isomerase, PDI, Prolyl 4-hydroxylase Subunit beta, Cellular Thyroid Hormone-binding Protein, p55, PO4DB, PDIA1, PDI, ERBA2L) (Biotin) Pab |
About Protein Disulfide Isomerase and Biotin
| Protein Disulfide Isomerase | This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008] |
|---|
Citations
| Additional Sources |
|
|---|
