BNP / APC /
BNP / APC /
Product Details
Supplier | US Biological | |
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Catalog #: | 212345-APC-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $865.00 | |
Antigen | BNP | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | APC | |
Target Species | Human | |
Applications | IHC, WB | |
Description | NPPB (B-type Natriuretic Peptide, Brain Natriuretic Peptide, BNP, Gamma-brain Natriuretic Peptide) (APC) Pab |
About BNP and APC
BNP | This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Aug 2020] | |
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APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |