BNP / HRP / 2D11
BNP / HRP / 2D11
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 130511-HRP-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $681.00 | |
| Antigen | BNP | |
| Clone | 2D11 | |
| Host | Mouse | |
| Isotype | IgG3 κ | |
| Conjugate | HRP | |
| Target Species | Human | |
| Applications | ELISA, IP, WB | |
| Description | NPPB (Natriuretic Peptides B, Gamma-brain Natriuretic Peptide) (HRP) Mab 2D11 |
About BNP and HRP
| BNP | This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Aug 2020] |
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Citations
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