FluoroFinder

	Supplier	MilliporeSigma
	Catalog #:	MABF518 (View supplier product page)
	Size	25 μg
	Price
	Antigen	CD11b
	Clone	M1/70
	Host	Rat
	Isotype	IgG2b κ
	Conjugate	violetFluor 450
	Target Species	Human, Mouse
	Applications	N/A

	CD11b	This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
	violetFluor 450	VioletFluor® 450 is a fluorophore from Tonbo with an excitation peak at 405 nm and an emission peak at 450 nm.

	Additional Sources

CD11b / violetFluor 450 / M1/70