MCP-1 / MaxLight 405 /
MCP-1 / MaxLight 405 /
Product Details
Supplier | US Biological | |
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Catalog #: | M1203-03E-ML405-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $908.00 | |
Antigen | MCP-1 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | MaxLight 405 | |
Target Species | Mouse | |
Applications | FC, Block/Neutralize, WB | |
Description | Macrophage, Monocyte Chemotactic Protein-1 (CCL2, Chemokine (C-C motif) ligand 2, C-C motif chemokine 2, GDCF-2, HC11, HSMCR30, MCAF, MCP1, MCP-1, MGC9434, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2, SMC-CF) (MaxLight 405) Pab |
About MCP-1 and MaxLight 405
MCP-1 | This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020] | |
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MaxLight 405 | MaxLight 405 is excited by the 405 laser and emission captured by the 450/50 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy. |