CD305 / PE / 7H26
CD305 / PE / 7H26
Product Details
Supplier | US Biological | |
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Catalog #: | L1100-01M-100TESTS (View supplier product page) | |
Size | 100 Tests | |
Price | $678.00 | |
Antigen | CD305 | |
Clone | 7H26 | |
Host | Mouse | |
Isotype | IgG2b | |
Conjugate | PE | |
Target Species | Human | |
Applications | FC | |
Description | LAIR-1 (Leukocyte-associated Ig-like Receptor-1) (PE) Mab 7H26 |
About CD305 and PE
CD305 | The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] | |
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PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |