KLRC1 / MaxLight 550 /
KLRC1 / MaxLight 550 /
Product Details
Supplier | US Biological | |
---|---|---|
Catalog #: | 211679-ML550-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $865.00 | |
Antigen | KLRC1 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | MaxLight 550 | |
Target Species | Human | |
Applications | IHC, WB | |
Description | KLRC1 (Killer Cell Lectin-like Receptor Subfamily C Member 1, CD159A, MGC13374, MGC59791, NKG2, NKG2A) (MaxLight 550) Pab |
About KLRC1 and MaxLight 550
KLRC1 | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015] | |
---|---|---|
MaxLight 550 | MaxLight 550 is excited by the 561 laser and emission captured by the 585/42 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy. |