FluoroFinder

	Supplier	US Biological
	Catalog #:	128899-ML550-100UL (View supplier product page)
	Size	100 μl
	Price	$681.00
	Antigen	KLRC1
	Clone	2C3
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	MaxLight 550
	Target Species	Human
	Applications	FC, IP
	Description	KLRC1 (Killer Cell Lectin-like Receptor Subfamily C Member 1, CD159 Antigen-like Family Member A, CD159a, NK Cell Receptor A, NKG2A, NKG2, NKG2-A/B-activating NK Receptor, NKG2-A/NKG2-B Type II Integral Membrane Protein, MGC13374, MGC59791) (MaxLight 550) Mab 2C3

	KLRC1	Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015]
	MaxLight 550	MaxLight 550 is excited by the 561 laser and emission captured by the 585/42 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy.

	Additional Sources

KLRC1 / MaxLight 550 / 2C3