KRT81 / Biotin /
KRT81 / Biotin /
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 548287-200UL (View supplier product page) | |
| Size | 200 μl | |
| Price | $488.00 | |
| Antigen | KRT81 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | IHC, WB | |
| Description | Keratin 81 (Biotin) Pab |
About KRT81 and Biotin
| KRT81 | The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008] |
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Citations
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