JMJD2D / FITC /
JMJD2D / FITC /
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 128683-FITC-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $718.00 | |
| Antigen | JMJD2D | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | FITC | |
| Target Species | Human | |
| Applications | WB | |
| Description | JMJD2D (Jumonji Domain Containing 2D, JMJD2D, KDM4D, Lysine-specific Demethylase 4D, JmjC Domain-containing Histone Demethylation Protein 3D, JHDM3D, FLJ10251, MGC141909) (FITC) Pab |
About JMJD2D and FITC
| JMJD2D | Enables histone H3-methyl-lysine-9 demethylase activity. Involved in histone H3-K9 demethylation. Acts upstream of or within several processes, including cellular response to ionizing radiation; positive regulation of chromatin binding activity; and positive regulation of double-strand break repair via nonhomologous end joining. Located in site of double-strand break. Biomarker of nephroblastoma. [provided by Alliance of Genome Resources, Apr 2022] | |
|---|---|---|
| FITC | Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark. |
Citations
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