PD-1 / APC-Cy7 / 29F.1A12
PD-1 / APC-Cy7 / 29F.1A12
Citations:
(19)
Product Details
Supplier | BioLegend | |
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Catalog #: | 135223 (View supplier product page) | |
Size | 25 μg | |
Price | $141.00 | |
Antigen | PD-1 | |
Clone | 29F.1A12 | |
Host | Rat | |
Isotype | IgG2a κ | |
Conjugate | APC-Cy7 | |
Target Species | Mouse | |
Applications | FC | |
Description | APC/Cyanine7 anti-mouse CD279 (PD-1) |
About PD-1 and APC-Cy7
PD-1 | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] | |
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APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |
Images
Citations
PMID 20453843 | ||
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Additional Sources |
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Reviews & Ratings
APC-Cy7 Excitation and Emission Spectra
$141.00
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