CD8a / Brilliant Violet 570 / RPA-T8
CD8a / Brilliant Violet 570 / RPA-T8
Citations:
(70)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 301038 (View supplier product page) | |
| Size | 100T | |
| Price | $418.00 | |
| Antigen | CD8a | |
| Clone | RPA-T8 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | Brilliant Violet 570 | |
| Target Species | Cynomolgus macaque, Human, Rhesus macaque | |
| Applications | FC | |
| Description | Brilliant Violet 570 anti-human CD8a |
About CD8a and Brilliant Violet 570
| CD8a | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] | |
|---|---|---|
| Brilliant Violet 570 | Brilliant™ Violet 570 (BV570) is a yellow-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 585/42 bandpass filter. BV570 has an excitation peak at 405 nm and an emission peak at 570 nm, and is spectrally similar to StarBright 570 (Bio-Rad). This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad. |
Images
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Human peripheral blood lymphocytes were stained with CD3 and CD8 (clone RPA-T8) Brilliant Violet 570™ (top) or mouse IgG1, κ Brilliant Violet 570™ isotype control (bottom). |
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Citations
| PMID 18490743 | ||
|---|---|---|
| PMID 19849846 | ||
| Additional Sources |
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Reviews & Ratings
Brilliant Violet 570 Excitation and Emission Spectra
$418.00
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