FluoroFinder

	Supplier	US Biological
	Catalog #:	128452-FITC-100UL (View supplier product page)
	Size	100 μl
	Price	$681.00
	Antigen	IL-23 R
	Clone	3D7
	Host	Mouse
	Isotype	IgG2a κ
	Conjugate	FITC
	Target Species	Human
	Applications	ELISA, WB
	Description	IL23R (IL-23R, IL-23 Receptor, IL-23 Receptor) (FITC) Mab 3D7

	IL-23 R	The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq, Jul 2008]
	FITC	Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.

	Additional Sources

IL-23 R / FITC / 3D7