CD194 / Brilliant Violet 605 / L291H4

Citations: (6)
Product Details
Supplier BioLegend
Catalog #: 359417 (View supplier product page)
Size 25T
Price $198.00
Antigen CD194
Clone L291H4
Host Mouse
Isotype IgG1 κ
Conjugate Brilliant Violet 605
Target Species Human
Applications FC
Description Brilliant Violet 605 anti-human CD194 (CCR4)
About CD194 and Brilliant Violet 605
CD194 The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]
Brilliant Violet 605 Brilliant™ Violet 605 (BV605) is an orange/red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 610/20 bandpass filter. BV605 has an excitation peak at 405 nm and an and emission peak at 603 nm. BV605 is most commonly used in flow cytometry and is spectrally similar to SuperBright 600 (Thermo Fisher), SuperNova v605 (Beckman Coulter) and StarBright Violet 610 (Bio-Rad). BV605 is considered to be relatively bright and should be used on antigens of moderate to low abudance. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad.
Images
  CD194 Brilliant Violet 605 BioLegend antibody anti target:Human host:Mouse isotype:IgG1 κ clone:L291H4

Human peripheral blood lymphocytes were stained with CD3 FITC and CD194 (clone L291H4) Brilliant Violet 605™ (top) or mouse IgG1, κ Brilliant Violet 605™ isotype control (bottom).

  CD194 Brilliant Violet 605 BioLegend antibody anti target:Human host:Mouse isotype:IgG1 κ clone:L291H4

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Brilliant Violet 605 Excitation and Emission Spectra