FluoroFinder

	Supplier	US Biological
	Catalog #:	247447-APC-100UL (View supplier product page)
	Size	100 μl
	Price	$681.00
	Antigen	IFN-alpha 2
	Clone	40
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	APC
	Target Species	Human
	Applications	ELISA, WB
	Description	IFNA2 (Interferon, alpha 2, IFNA, INFA2, MGC125764, MGC125765) (APC) Mab 40

	IFN-alpha 2	This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach. [provided by RefSeq, Aug 2020]
	APC	Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.

	Additional Sources

IFN-alpha 2 / APC / 40