PD-1 / Brilliant Violet 510 / EH12.2H7
PD-1 / Brilliant Violet 510 / EH12.2H7
Citations:
(15)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 329932 (View supplier product page) | |
| Size | 100T | |
| Price | $402.00 | |
| Antigen | PD-1 | |
| Clone | EH12.2H7 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | Brilliant Violet 510 | |
| Target Species | Human | |
| Applications | FC | |
| Description | Brilliant Violet 510 anti-human CD279 (PD-1) |
About PD-1 and Brilliant Violet 510
| PD-1 | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| Brilliant Violet 510 | Brilliant™ Violet 510 (BV510) is a green-emitting non-tandem polymer fluorophore that can be excited by the 405 nm Violet laser and collected using a 510/50 bandpass filter. BV510 has an excitation peak at 405 nm and an emission peak at 510 nm, and is similar to StarBright Violet 515 (Bio-Rad). BV510 is most often used in flow cytometry due to its improved signal-to-noise over alternatives like V500 and AmCyan. This dye is part of the Brilliant™ Violet dye line. BV510 and BV480 are the only dyes in the Brilliant™ Violet dye family that are not tandem fluorophores based off the BV421 polymer core, but they have nearly the same maximum excitation. |
Images
|
PHA-stimulated (day-3) human peripheral blood lymphocytes were stained with CD279 (clone EH12.2H7) Brilliant Violet 510™ (filled histogram) or mouse IgG1, κ Brilliant Violet 510™ isotype control (open histogram). |
Citations
| PMID 18829748 | ||
|---|---|---|
| PMID 18981087 | ||
| PMID 19553327 | ||
| PMID 19889785 | ||
| PMID 20100932 | ||
| PMID 21398606 | ||
| PMID 21562156 | ||
| Additional Sources |
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Reviews & Ratings
Brilliant Violet 510 Excitation and Emission Spectra
$402.00
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