HMGB1 / PE / 3E8

Citations: (6)
Product Details
Supplier BioLegend
Catalog #: 651404 (View supplier product page)
Size 100T
Price $347.00
Antigen HMGB1
Clone 3E8
Host Mouse
Isotype IgG2b κ
Conjugate PE
Target Species Human, Mouse, Rat
Applications ICS
Description PE anti-HMGB1
About HMGB1 and PE
HMGB1 This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Images
  HMGB1 PE BioLegend antibody anti target:Human, Mouse, Rat host:Mouse isotype:IgG2b κ clone:3E8

Hela cells were fixed and permeabilized with FOXP3 Fix/Perm Buffer Set, and then stained with anti-HMGB1 (clone 3E8) PE (filled histogram) or mouse IgG2b, κ PE isotype control (open histogram).

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PE Excitation and Emission Spectra