EGF Receptor / PE-Cy7 / AY13
EGF Receptor / PE-Cy7 / AY13
Citations:
(3)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 352909 (View supplier product page) | |
| Size | 25T | |
| Price | $176.00 | |
| Antigen | EGF Receptor | |
| Clone | AY13 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | PE-Cy7 | |
| Target Species | Human | |
| Applications | FC | |
| Description | PE/Cyanine7 anti-human EGFR |
About EGF Receptor and PE-Cy7
| EGF Receptor | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020] | |
|---|---|---|
| PE-Cy7 | PE-Cyanine®7 (PE-Cy7, RPE-Cy7) is a far red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy7. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy7, which emits light that can be captured with a 780/60 nm bandpass filter. PE-CY7 has an excitation peak at 565 nm and an emission peak at 778 nm, and is a suitable alternative to PE-Vio®770 (Miltenyi) and cFluor BYG781 (Cytek). |
Images
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Human cervical cancer cell line, Hela, was stained with EGFR (clone AY13) PE/Cy7 (filled histogram) or mouse IgG1, κ PE/Cy7 isotype control (open histogram). |
Citations
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Reviews & Ratings
PE-Cy7 Excitation and Emission Spectra
$176.00
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