FluoroFinder

	Supplier	BioLegend
	Catalog #:	353423 (View supplier product page)
	Size	25T
	Price	$215.00
	Antigen	CCR6
	Clone	G034E3
	Host	Mouse
	Isotype	IgG2b κ
	Conjugate	Brilliant Violet 510
	Target Species	Cynomolgus macaque, Human, Rhesus macaque
	Applications	FC
	Description	Brilliant Violet 510 anti-human CD196 (CCR6)

	CCR6	This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
	Brilliant Violet 510	Brilliant™ Violet 510 (BV510) is a green-emitting non-tandem polymer fluorophore that can be excited by the 405 nm Violet laser and collected using a 510/50 bandpass filter. BV510 has an excitation peak at 405 nm and an emission peak at 510 nm, and is similar to StarBright Violet 515 (Bio-Rad). BV510 is most often used in flow cytometry due to its improved signal-to-noise over alternatives like V500 and AmCyan. This dye is part of the Brilliant™ Violet dye line. BV510 and BV480 are the only dyes in the Brilliant™ Violet dye family that are not tandem fluorophores based off the BV421 polymer core, but they have nearly the same maximum excitation.

		Human peripheral blood lymphocytes were stained with CD19 APC and CD196 (clone G034E3) Brilliant Violet 510™ (top) or mouse IgG2b, κ Brilliant Violet 510™ isotype control (bottom).