CD49f / PE-Cy7 / GoH3

Citations: (25)
Product Details
Supplier BioLegend
Catalog #: 313621 (View supplier product page)
Size 25T
Price $159.00
Antigen CD49f
Clone GoH3
Host Rat
Isotype IgG2a κ
Conjugate PE-Cy7
Target Species Cynomolgus macaque, Human, Mouse, Rhesus macaque
Applications FC
Description PE/Cyanine7 anti-human/mouse CD49f
About CD49f and PE-Cy7
CD49f The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
PE-Cy7 PE-Cyanine®7 (PE-Cy7, RPE-Cy7) is a far red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy7. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy7, which emits light that can be captured with a 780/60 nm bandpass filter. PE-CY7 has an excitation peak at 565 nm and an emission peak at 778 nm, and is a suitable alternative to PE-Vio®770 (Miltenyi) and cFluor BYG781 (Cytek).
Images
  CD49f PE-Cy7 BioLegend antibody anti target:Cynomolgus macaque, Human, Mouse, Rhesus macaque host:Rat isotype:IgG2a κ clone:GoH3

Human peripheral blood lymphocytes were stained with anti-human/mouse CD49f (clone GoH3) PE/Cy7 (filled histogram) or rat IgG2a, κ PE/Cy7 isotype control (open histogram).

Citations
Reviews & Ratings
PE-Cy7 Excitation and Emission Spectra