CCR6 / Brilliant Violet 605 / G034E3

Citations: (20)
Product Details
Supplier BioLegend
Catalog #: 353420 (View supplier product page)
Size 100T
Price $451.00
Antigen CCR6
Clone G034E3
Host Mouse
Isotype IgG2b κ
Conjugate Brilliant Violet 605
Target Species Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description Brilliant Violet 605 anti-human CD196 (CCR6)
About CCR6 and Brilliant Violet 605
CCR6 This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Brilliant Violet 605 Brilliant™ Violet 605 (BV605) is an orange/red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 610/20 bandpass filter. BV605 has an excitation peak at 405 nm and an and emission peak at 603 nm. BV605 is most commonly used in flow cytometry and is spectrally similar to SuperBright 600 (Thermo Fisher), SuperNova v605 (Beckman Coulter) and StarBright Violet 610 (Bio-Rad). BV605 is considered to be relatively bright and should be used on antigens of moderate to low abudance. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad.
Images
  CCR6 Brilliant Violet 605 BioLegend antibody anti target:Cynomolgus macaque, Human, Rhesus macaque host:Mouse isotype:IgG2b κ clone:G034E3

Human peripheral blood lymphocytes were stained with CD19 PE and CD196 (clone G034E3) Brilliant Violet 605™.
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Brilliant Violet 605 Excitation and Emission Spectra