ErbB4 / MaxLight 550 /
ErbB4 / MaxLight 550 /
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | 036514-ML550-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $711.00 | |
| Antigen | ErbB4 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | MaxLight 550 | |
| Target Species | Human | |
| Applications | FC, WB | |
| Description | HER4, CT (Y1162) (ERBB4,HER4,Receptor tyrosine-protein kinase erbB-4) (MaxLight 550) Pab |
About ErbB4 and MaxLight 550
| ErbB4 | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| MaxLight 550 | MaxLight 550 is excited by the 561 laser and emission captured by the 585/42 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy. |
Citations
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