CD127 / PE-Cy5 / A7R34

Citations: (17)
Product Details
Supplier BioLegend
Catalog #: 135016 (View supplier product page)
Size 200UG
Price $387.00
Antigen CD127
Clone A7R34
Host Rat
Isotype IgG2a κ
Conjugate PE-Cy5
Target Species Mouse
Applications FC
Description PE/Cyanine5 anti-mouse CD127 (IL-7Ralpha)
About CD127 and PE-Cy5
CD127 The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015]
PE-Cy5 PE-Cyanine®5 (PE-Cy5) is a red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy5. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy5. PE-Cy5 has an excitation peak at 496 nm and an emission peak at 667 nm.
Images
  CD127 PE-Cy5 BioLegend antibody anti target:Mouse host:Rat isotype:IgG2a κ clone:A7R34

C57BL/6 mouse splenocytes stained with CD3 (145-2C11) FITC and A7R34 PE/Cy5 (top) or rat IgG2a,κ PE/Cy5 isotype control (bottom)

  CD127 PE-Cy5 BioLegend antibody anti target:Mouse host:Rat isotype:IgG2a κ clone:A7R34

Citations
PMID 21209281
PMID 21653324
Additional
Sources
Reviews & Ratings
PE-Cy5 Excitation and Emission Spectra