CCR6 / Alexa Fluor 647 / 29-2L17

Citations: (5)
Product Details
Supplier BioLegend
Catalog #: 129807 (View supplier product page)
Size 25 μg
Price $147.00
Antigen CCR6
Clone 29-2L17
Host Armenian Hamster
Isotype IgG
Conjugate Alexa Fluor 647
Target Species Mouse
Applications FC
Description Alexa Fluor 647 anti-mouse CD196 (CCR6)
About CCR6 and Alexa Fluor 647
CCR6 This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
Images
  CCR6 Alexa Fluor 647 BioLegend antibody anti target:Mouse host:Armenian Hamster isotype:IgG clone:29-2L17

C57BL/6 splenocytes stained with RA3-6B2 (B220) PE and 29-2L17 Alexa Fluor® 647

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Alexa Fluor 647 Excitation and Emission Spectra