CD326 / PE / G8.8

Citations: (51)
Product Details
Supplier BioLegend
Catalog #: 118206 (View supplier product page)
Size 200UG
Price $329.00
Antigen CD326
Clone G8.8
Host Rat
Isotype IgG2a κ
Conjugate PE
Target Species Mouse
Applications FC
Description PE anti-mouse CD326 (Ep-CAM)
About CD326 and PE
CD326 This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Images
  CD326 PE BioLegend antibody anti target:Mouse host:Rat isotype:IgG2a κ clone:G8.8

TE-71 (mouse thymic epithelial stromal cell line) cells were stained with CD326 (clone G8.8) PE (filled histogram) or rat IgG2a, κ PE isotype control (open histogram).

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PE Excitation and Emission Spectra