FluoroFinder

	Supplier	BioLegend
	Catalog #:	301316 (View supplier product page)
	Size	25 μg
	Price	$112.00
	Antigen	CD11b
	Clone	ICRF44
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	Pacific Blue
	Target Species	Cynomolgus macaque, Human, Rhesus macaque
	Applications	FC
	Description	Pacific Blue anti-human CD11b

	CD11b	This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
	Pacific Blue	Pacific Blue® (Pac Blue, PacBlue) is a blue-emitting organic fluorophore that can be excited by the 405 nm Violet laser and captured with a 450/50 nm bandpass filter. Pacific Blue has an excititaion peak at 401 nm and an emission peak at 452 nm.