GAD65 / APC / 2Q61, GAD-6
GAD65 / APC / 2Q61, GAD-6
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | G7116-05-APC-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $925.00 | |
| Antigen | GAD65 | |
| Clone | 2Q61, GAD-6 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | APC | |
| Target Species | Rat | |
| Applications | IHC, WB | |
| Description | Glutamic Acid Decarboxylase (GAD) (APC) Mab 2Q61, GAD-6 |
About GAD65 and APC
| GAD65 | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
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