Glutamate Dehydrogenase / HRP / 13k26
Glutamate Dehydrogenase / HRP / 13k26
Product Details
Supplier | US Biological | |
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Catalog #: | 143066-HRP-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $1,064.00 | |
Antigen | Glutamate Dehydrogenase | |
Clone | 13k26 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | HRP | |
Target Species | Human | |
Applications | ELISA | |
Description | Glutamate Dehydrogenase (GDH) (HRP) Mab 13k26 |
About Glutamate Dehydrogenase and HRP
Glutamate Dehydrogenase | This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016] |
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