CD357 / Biotin / 11K7
CD357 / Biotin / 11K7
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | G2035-08Q-100UG (View supplier product page) | |
| Size | 100 μg | |
| Price | $602.00 | |
| Antigen | CD357 | |
| Clone | 11K7 | |
| Host | Mouse | |
| Isotype | IgM κ | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | ELISA, FC | |
| Description | GITR (Glucocorticoid-induced TNFR-related Protein, Activation-inducible TNFR Family Receptor, AITR, CD357, Tumor Necrosis Factor Receptor Superfamily Member 18, TNFRSF18, UNQ319/PRO364) (Biotin) Mab 11K7 |
About CD357 and Biotin
| CD357 | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011] |
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Citations
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