CD357 / PE / YGITR 765

Citations: (7)
Product Details
Supplier BioLegend
Catalog #: 120208 (View supplier product page)
Size 100 μg
Price $323.00
Antigen CD357
Clone YGITR 765
Host Rat
Isotype IgG2b κ
Conjugate PE
Target Species Mouse
Applications FC
Description PE anti-mouse CD357 (GITR)
About CD357 and PE
CD357 This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Images
  CD357 PE BioLegend antibody anti target:Mouse host:Rat isotype:IgG2b κ clone:YGITR 765

C57BL/6 mouse splenocytes stained with CD4 APC and YGITR 765 PE

Citations
PMID 18407967
Additional
Sources
Reviews & Ratings
PE Excitation and Emission Spectra