GFR alpha-1 / HRP / 1G4

Product Details
Supplier US Biological
Catalog #: 246564-HRP-100UL (View supplier product page)
Size 100 μl
Price $681.00
Antigen GFR alpha-1
Clone 1G4
Host Mouse
Isotype IgG2a κ
Conjugate HRP
Target Species Human
Applications ELISA, IF, WB
Description GFRA1 (GDNF Family Receptor alpha 1, GDNFR, GDNFRA, GFR-ALPHA-1, MGC23045, RET1L, RETL1, TRNR1) (HRP) Mab 1G4
About GFR alpha-1 and HRP
GFR alpha-1 This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Citations
Additional
Sources
Reviews & Ratings
HRP Excitation and Emission Spectra