GFR alpha-1 / HRP /
GFR alpha-1 / HRP /
Product Details
Supplier | US Biological | |
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Catalog #: | 210989-HRP-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $865.00 | |
Antigen | GFR alpha-1 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | HRP | |
Target Species | Human | |
Applications | IF, IHC, WB | |
Description | GFRA1 (GDNF Family Receptor alpha-1, GDNFR, RET1L, RETL1, TRNR1, GDNFRA, GFR-ALPHA-1) (HRP) Pab |
About GFR alpha-1 and HRP
GFR alpha-1 | This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016] |
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