CD161 / Alexa Fluor 647 / PK136

Citations: (10)
Product Details
Supplier BioLegend
Catalog #: 108719 (View supplier product page)
Size 25 μg
Price $101.00
Antigen CD161
Clone PK136
Host Mouse
Isotype IgG2a κ
Conjugate Alexa Fluor 647
Target Species Mouse
Applications FC
Description Alexa Fluor 647 anti-mouse NK-1.1
About CD161 and Alexa Fluor 647
CD161 Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
Images
  CD161 Alexa Fluor 647 BioLegend antibody anti target:Mouse host:Mouse isotype:IgG2a κ clone:PK136

C57BL/6 mouse splenocytes were stained with CD49b (DX5) PE and NK1.1 (clone PK136) Alexa Fluor® 647 (top) or mouse IgG2a Alexa Fluor® 647 isotype control (bottom).

  CD161 Alexa Fluor 647 BioLegend antibody anti target:Mouse host:Mouse isotype:IgG2a κ clone:PK136

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Alexa Fluor 647 Excitation and Emission Spectra