GAD1 / MaxLight 750 /

Product Details
Supplier US Biological
Catalog #: 127089-ML750-100UL (View supplier product page)
Size 100 μl
Price $718.00
Antigen GAD1
Clone
Host Rabbit
Isotype IgG
Conjugate MaxLight 750
Target Species Human
Applications WB
Description GAD1 (Glutamate Decarboxylase 1, 67kD Glutamic Acid Decarboxylase, GAD-67, Glutamate Decarboxylase 67kD Isoform, GAD, GAD67) (MaxLight 750) Pab
About GAD1 and MaxLight 750
GAD1 This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
MaxLight 750 MaxLight 750 is excited by the laser and emission captured by the 780/60 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy.
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MaxLight 750 Excitation and Emission Spectra