CD62L / PerCP-Cy5.5 / MEL-14

Citations: (51)
Product Details
Supplier BioLegend
Catalog #: 104432 (View supplier product page)
Size 100 μg
Price $323.00
Antigen CD62L
Clone MEL-14
Host Rat
Isotype IgG2a κ
Conjugate PerCP-Cy5.5
Target Species Mouse
Applications FC
Description PerCP/Cyanine5.5 anti-mouse CD62L
About CD62L and PerCP-Cy5.5
CD62L This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
PerCP-Cy5.5 PerCP-Cyanine® 5.5 (PerCP-Cy5.5) is a red-emitting tandem fluorophore that was originally designed to make the PerCP fluorophore more stable and increase signal intensity. The donor molecule, PerCP can be excited by the 488-nm blue laser and and transfers energy to the acceptor molecule, Cy5.5, which emitts light that can be captured with a 695/40 nm bandpass filter. PerCP-Cy5.5 has an excitation peak at 482 nm and an emission peak at 695 nm. There are superior alternatives to PerCP and PerCP-Cy5.5 including RealBlue 705 (BD Biosciences), NovaFluor Blue 690 or PerCP-eFluor™ 710.
Citations
Reviews & Ratings
PerCP-Cy5.5 Excitation and Emission Spectra