CD44 / Alexa Fluor 488 / IM7

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Product Details
Supplier BioLegend
Catalog #: 103015 (View supplier product page)
Size 25 μg
Price $101.00
Antigen CD44
Clone IM7
Host Rat
Isotype IgG2b κ
Conjugate Alexa Fluor 488
Target Species Human, Mouse
Applications FC, Spatial Biology, ICC, IHC-P
Description Alexa Fluor 488 anti-mouse/human CD44
About CD44 and Alexa Fluor 488
CD44 The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
Images
  CD44 Alexa Fluor 488 BioLegend antibody anti target:Human, Mouse host:Rat isotype:IgG2b κ clone:IM7

C57BL/6 mouse splenocytes stained with IM7 Alexa Fluor® 488

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Alexa Fluor 488 Excitation and Emission Spectra