CD11a / PE / M17/4

Citations: (14)
Product Details
Supplier BioLegend
Catalog #: 101107 (View supplier product page)
Size 50 μg
Price $104.00
Antigen CD11a
Clone M17/4
Host Rat
Isotype IgG2a κ
Conjugate PE
Target Species Mouse
Applications FC
Description PE anti-mouse CD11a
About CD11a and PE
CD11a ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Images
  CD11a PE BioLegend antibody anti target:Mouse host:Rat isotype:IgG2a κ clone:M17/4

C57BL/6 mouse splenocytes stained with M17/4 PE

Citations
PMID 25108241
Additional
Sources
Reviews & Ratings
PE Excitation and Emission Spectra