CCR6 / Brilliant Violet 650 / G034E3
CCR6 / Brilliant Violet 650 / G034E3
Citations:
(6)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 353426 (View supplier product page) | |
| Size | 100T | |
| Price | $446.00 | |
| Antigen | CCR6 | |
| Clone | G034E3 | |
| Host | Mouse | |
| Isotype | IgG2b κ | |
| Conjugate | Brilliant Violet 650 | |
| Target Species | Cynomolgus macaque, Human, Rhesus macaque | |
| Applications | FC | |
| Description | Brilliant Violet 650 anti-human CD196 (CCR6) |
About CCR6 and Brilliant Violet 650
| CCR6 | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| Brilliant Violet 650 | Brilliant™ Violet 650 (BV650) is a red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 660/20 bandpass filter. BV650 has an excitation peak at 405 nm and an emission peak at 645 nm. Due to its unique Stokes shift, not many dyes have identical excitation and emission spectrums, but the nearest alternatives include SuperBright 645, Qdot® 655 and eFluor™ 650NC (ThermoFisher). BV650 exhibits a medium level of brightness and is most often used in flow cytometry, specifically, it is an alternative to nanocrystals used for intracellular flow. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad. |
Images
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Human peripheral lymphocytes were stained with CD19 PE and CCR6 (clone G034E3) Brilliant Violet 650™ (top) or mouse IgG2b, κ Brilliant Violet 650™ isotype control (bottom). |
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Citations
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Reviews & Ratings
Brilliant Violet 650 Excitation and Emission Spectra
$446.00
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