CD326 / PE-Cy7 / 9C4

Citations: (20)
Product Details
Supplier BioLegend
Catalog #: 324222 (View supplier product page)
Size 100T
Price $382.00
Antigen CD326
Clone 9C4
Host Mouse
Isotype IgG2b κ
Conjugate PE-Cy7
Target Species Human
Applications FC
Description PE/Cyanine7 anti-human CD326 (Ep-CAM)
About CD326 and PE-Cy7
CD326 This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
PE-Cy7 PE-Cyanine®7 (PE-Cy7, RPE-Cy7) is a far red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy7. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy7, which emits light that can be captured with a 780/60 nm bandpass filter. PE-CY7 has an excitation peak at 565 nm and an emission peak at 778 nm, and is a suitable alternative to PE-Vio®770 (Miltenyi) and cFluor BYG781 (Cytek).
Images
  CD326 PE-Cy7 BioLegend antibody anti target:Human host:Mouse isotype:IgG2b κ clone:9C4

HT-29 cells were stained with CD326 (EpCAM) PE/Cy7 (filled histogram) or mouse IgG2b, κ PE/Cy7 isotype control (open histogram).

Citations
PMID 20615947
Additional
Sources
Reviews & Ratings
PE-Cy7 Excitation and Emission Spectra