CD326 / Brilliant Violet 605 / G8.8

Citations: (27)
Product Details
Supplier BioLegend
Catalog #: 118227 (View supplier product page)
Size 50 μg
Price $297.00
Antigen CD326
Clone G8.8
Host Rat
Isotype IgG2a κ
Conjugate Brilliant Violet 605
Target Species Mouse
Applications FC
Description Brilliant Violet 605 anti-mouse CD326 (Ep-CAM)
About CD326 and Brilliant Violet 605
CD326 This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
Brilliant Violet 605 Brilliant™ Violet 605 (BV605) is an orange/red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 610/20 bandpass filter. BV605 has an excitation peak at 405 nm and an and emission peak at 603 nm. BV605 is most commonly used in flow cytometry and is spectrally similar to SuperBright 600 (Thermo Fisher), SuperNova v605 (Beckman Coulter) and StarBright Violet 610 (Bio-Rad). BV605 is considered to be relatively bright and should be used on antigens of moderate to low abudance. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad.
Images
  CD326 Brilliant Violet 605 BioLegend antibody anti target:Mouse host:Rat isotype:IgG2a κ clone:G8.8

TE-71 (mouse thymic epithelial stromal cell line) was stained with CD326 (clone G8.8) Brilliant Violet 605™ (filled histogram) or rat IgG2a, κ Brilliant Violet 605™ isotype control (open histogram).

Citations
Reviews & Ratings
Brilliant Violet 605 Excitation and Emission Spectra