CD326 / Brilliant Violet 421 / G8.8

Citations: (48)
Product Details
Supplier BioLegend
Catalog #: 118225 (View supplier product page)
Size 50 μg
Price $252.00
Antigen CD326
Clone G8.8
Host Rat
Isotype IgG2a κ
Conjugate Brilliant Violet 421
Target Species Mouse
Applications FC
Description Brilliant Violet 421 anti-mouse CD326 (Ep-CAM)
About CD326 and Brilliant Violet 421
CD326 This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
Brilliant Violet 421 Brilliant™ Violet 421 (BV421) is a Violet-emitting non-tandem polymer fluorophore that can be excited by the 405 nm Violet laser and collected using a 450/50 bandpass filter. BV421 has an excitation peak at 405 nm and an emission peak at 421 nm, and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. Other similar fluorophores include SuperNova V428 (Beckman Coulter), StarBright Violet 440 (Bio-Rad) and SuperBright 436 (Thermo Fisher). BV421 is very bright and is most commonly used for flow cytometry. BV421 is very photo- and fixative stable. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dyes from Beckman Coulter and StarBright dyes from Bio-Rad.
Images
  CD326 Brilliant Violet 421 BioLegend antibody anti target:Mouse host:Rat isotype:IgG2a κ clone:G8.8

TE-71 (mouse thymic epithelial stromal cell line) was stained with CD326 (clone G8.8) Brilliant Violet 421™ (filled histogram) or rat IgG2a, κ Brilliant Violet 421™ isotype control (open histogram).

Citations
Reviews & Ratings
Brilliant Violet 421 Excitation and Emission Spectra