FluoroFinder

	Supplier	US Biological
	Catalog #:	E3451-40M-ML550-100UL (View supplier product page)
	Size	100 μl
	Price	$789.00
	Antigen	ErbB4
	Clone	9H232, HFR1/2G4
	Host	Mouse
	Isotype	IgG2b
	Conjugate	MaxLight 550
	Target Species	Human
	Applications	IHC, IP, WB
	Description	erbB4 (c-erbB4, HER4) (MaxLight 550) Mab 9H232, HFR1/2G4

	ErbB4	This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
	MaxLight 550	MaxLight 550 is excited by the 561 laser and emission captured by the 585/42 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy.

	Additional Sources

ErbB4 / MaxLight 550 / 9H232, HFR1/2G4