CD62L / Brilliant Violet 650 / DREG-56
CD62L / Brilliant Violet 650 / DREG-56
Citations:
(5)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 304832 (View supplier product page) | |
| Size | 100T | |
| Price | $396.00 | |
| Antigen | CD62L | |
| Clone | DREG-56 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | Brilliant Violet 650 | |
| Target Species | Human | |
| Applications | FC | |
| Description | Brilliant Violet 650 anti-human CD62L |
About CD62L and Brilliant Violet 650
| CD62L | This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009] | |
|---|---|---|
| Brilliant Violet 650 | Brilliant™ Violet 650 (BV650) is a red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 660/20 bandpass filter. BV650 has an excitation peak at 405 nm and an emission peak at 645 nm. Due to its unique Stokes shift, not many dyes have identical excitation and emission spectrums, but the nearest alternatives include SuperBright 645, Qdot® 655 and eFluor™ 650NC (ThermoFisher). BV650 exhibits a medium level of brightness and is most often used in flow cytometry, specifically, it is an alternative to nanocrystals used for intracellular flow. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad. |
Images
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Human peripheral blood lymphocytes were stained with CD62L (clone DREG-56) Brilliant Violet 650™ (filled histogram) or mouse IgG1 Brilliant Violet 650™ isotype control (open histogram). |
Citations
| PMID 18490743 | ||
|---|---|---|
| PMID 18941247 | ||
| PMID 19849846 | ||
| PMID 20512127 | ||
| PMID 21976773 | ||
| PMID 23948971 | ||
| PMID 23999103 | ||
| Additional Sources |
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Reviews & Ratings
Brilliant Violet 650 Excitation and Emission Spectra
$396.00
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