EphB2 / Biotin / 4D1
EphB2 / Biotin / 4D1
Product Details
Supplier | US Biological | |
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Catalog #: | 126388-Biotin-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $681.00 | |
Antigen | EphB2 | |
Clone | 4D1 | |
Host | Mouse | |
Isotype | IgG2a κ | |
Conjugate | Biotin | |
Target Species | Human | |
Applications | ELISA, WB | |
Description | EphB2 (Ephrin Type-B Receptor 2, DRT, EPH-like Kinase 5, EK5, hEK5, ERK, Renal Carcinoma Antigen NY-REN-47, Tyrosine-protein Kinase TYRO5, Tyrosine-protein Kinase Receptor EPH-3, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5) (Biotin) Mab 4D1 |
About EphB2 and Biotin
EphB2 | This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] |
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