HuR / Biotin /
HuR / Biotin /
Product Details
Supplier | US Biological | |
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Catalog #: | 210664-Biotin-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $865.00 | |
Antigen | HuR | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Biotin | |
Target Species | Human | |
Applications | IF, IHC, WB | |
Description | ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-like 1 (Hu Antigen R), HUR, Hua, MelG, ELAV1) (Biotin) Pab |
About HuR and Biotin
HuR | The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012] |
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