4EBP1 / APC /
4EBP1 / APC /
Product Details
Supplier | US Biological | |
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Catalog #: | 210653-APC-100UL (View supplier product page) | |
Size | 100 μl | |
Price | $865.00 | |
Antigen | 4EBP1 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | APC | |
Target Species | Human | |
Applications | IHC, WB | |
Description | EIF4EBP1 (Eukaryotic Translation Initiation Factor 4E Binding Protein 1, 4E-BP1, 4EBP1, BP-1, MGC4316, PHAS-I) (APC) Pab |
About 4EBP1 and APC
4EBP1 | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008] | |
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APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |