CD263 / Biotin / 2B8
CD263 / Biotin / 2B8
Product Details
| Supplier | US Biological | |
|---|---|---|
| Catalog #: | D1499-01A-Biotin-100UL (View supplier product page) | |
| Size | 100 μl | |
| Price | $788.00 | |
| Antigen | CD263 | |
| Clone | 2B8 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | IP | |
| Description | DcR1 (Decoy Receptor 1, CD263, Lymphocyte Inhibitor of TRAIL, LIT, TNF Related Apoptosis Inducing Ligand Receptor 3, TRAIL Receptor 3, TRAIL R3, TRAILR3, TRAIL-R3, TRAIL Receptor Without An Intracellular Domain, TRID, Tumor Necrosis Factor Receptor Superfamily Member 10C, TNFRSF10C) (Biotin) Mab 2B8 |
About CD263 and Biotin
| CD263 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008] |
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Citations
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